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Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with Recurrent development to myelofibrosis.Ac-DEVD-CHO acetate (169332-60-9 free base)V617F allele mutation burden over the MPN subtypes of individuals confirmed a heterogeneous trend, five of 36 evaluable individuals experienced an allele burden reduction of �?fifty% at any tim